March 29, 2023: Day 0

Friday, March 31, 2023 · by kathy howe

Day 0 arrived and while I was excited, I tried not to “make a big deal” about it because we all know how teenagers *love* it when their moms make a big deal. 😂

Even though he’s **getting stem cells** and will have a reconstituted immune system 🤯 — and that’s a BFD — the biggest of all of our lives — everything was steady as she goes over here, which was a tribute to Sam and his awesomeness.  And that was reflected in my favorite photo of the afternoon: him holding his cell phone just like any other day while the stem cells used the old school method of gravity to find their new home.

The top line is he did great. There was a tiny chance that he could have an allergic reaction to it just like any other blood product so they monitor heavily the first 15 mins. And subsequent 15 minute segments too.  Thankfully nothing.

Around 4 pm, the stem cells arrived in a very non-high tech container: literally a hand held cooler with a flip top that many people carry their lunches in. It was carried by a woman in a white lab coat. There is a serious hand off procedure that includes the lab scientist going over all the information with the attending doctor: they ask all of Sam’s info (birthday, medical record number, etc — everything that the bag of stem cells has printed on it and it *has to match* hence all the checking and re-checking.  And then they go over the same for my information, which is also listed on the bag: the scientist asking the doctor and the doctor reading the bag’s label and answering.

Then the doctor signs off that he (in our case) received it and it’s all kopacetic (to quote my dear, 86 year old father ❤️).

Then they do that process again but the nurse is the recipient and the doctor asks her (in our case) the questions.

Dr. Shyr said that I was able to give Sam 8 million cells per kilo of Sam’s weight which is within the target amount (Dr. Bertaina, who runs the SCT program here, likes to get 10 million/kilo but there are other factors that contribute to getting to 10 million and so 8, 9 or 10 or more is considered enough (There is no correlation between more stem cells and better long term outcomes or fewer instances of  infection or less graft vs. host disease or higher rates of stem cell rejection. The only correlation is with faster time to engraftment).

Watching my cells travel by gravity down the tube and into Sam’s body was very memorable (they only use gravity, no pump (except Sam’s heart, of course) because a pump can damage the cells). And the entire process only took 30 mins!?!?!?! 🤯. Thinking about part of me finding a home in him and restoring his immune system makes me eternally grateful that he was born at the time he was, that we we have access to a world class medical center and it’s only 5 mins away, and we get to both benefit from and participate in moving science forward in the form of clinical trials. Humbling. Gratitude-filled. Steady as she goes with my own sprinkle of excitement on top.

Hopeful.  On to Day 1.

#FULeukemia

#LFGStemCells

#TeamSamStrong

♥ 50 hearts

23 comments

Dana Lilly · Friday, March 31, 2023
Thanks for the detailed update. It’s amazing what science can do these days. Much gratitude to everyone, including mom’s stem cells. Sounds like an awesome combination ❤️. Sending lots of love and many hugs to all 🥰
John Lilly · Friday, March 31, 2023
Great update, Kathy. I was just bugging John for an update. We’re very excited, too, that it went well and Sam’s body can now work on rebuilding its immune system. It is a BFD kind of day.
Erin Lavik · Friday, March 31, 2023
That is truly extraordinary. Thinking of you all
Erica Hinton · Friday, March 31, 2023
Amazing! That’s a pretty incredible image—those cells traveling from mother to son♥️
Cindy McLaughlin · Friday, March 31, 2023
A lotta love filled those stem cells - I'm sure Sam felt that too. You're wonderful parents.
Richard Morgan · Friday, March 31, 2023
So glad to read this positive update. Quite incredible this mom and son collab! #samstrong
Jim Mack · Friday, March 31, 2023
I just love love love science and medicine and what it is doing to make Sam ‘not sick again’❤️
Claudia Hung · Friday, March 31, 2023
It warms my heart to read this. Go stem cells! ❤️
Sean White · Friday, March 31, 2023
Sounds like an awesome mom and exciting Day 0!
J'Ann Schoonmaker Allen · Friday, March 31, 2023
Wow!
Paulo Correia · Friday, March 31, 2023
As this is the continuation of a fantastic journey, I'm not afraid to share that this update made me tear up. To literally give life, once again, to your child, is a modern miracle. Way to go, neighbor! :)
kathy howe · Friday, March 31, 2023
❤️❤️❤️
Ellen Levy · Friday, March 31, 2023
So amazing in so many ways. BFD Day indeed. Hurray for gravity. For awesome mom stem cells. For Sam’s I-got-this-just-pass-me-my-cell-phone attitude. For an incredible family support system. And for science.
Jessica White · Friday, March 31, 2023
Let's sprinkle LOTSof excitement on top! What a frickin miracle. I remember being in the room at Stanford when my mom received her lil ziploc bog of stem cells from Europe. Cheering for you all!!
kathy howe · Friday, March 31, 2023
❤️❤️❤️❤️
Joe Beninato · Friday, March 31, 2023
It must be a surreal/amazing experience as a mom to help heal the child you brought into the world.
kathy howe · Friday, March 31, 2023
Very much so. So very empowering and surreal.
Bryan Rollins · Friday, March 31, 2023
I've never been more excited about gravity and all it's meanings. What a day. You will celebrate this anniversary!
David Hornik · Friday, March 31, 2023
#teamsamstrong
Joe Shortt · Friday, March 31, 2023
The science is incredible and so are all of you guys !
Brendan Baker · Friday, March 31, 2023
This is just amazing to read, for several reasons. What a day.
Palon Shuster · Friday, March 31, 2023
This warms my heart so much.
Lisa Allie · Friday, March 31, 2023
I’m sending lots of positive thoughts and wishes for an uneventful and quick engraftment! It’s a big day indeed!